Value Chain for Drug Discovery
( Pharmaceutical Innovation Value Chain )
(1) Allergy and Malaria (2005-2006)
Funded by MEXT (Ministry of Education, Culture, Sports, Science and Technology) $1M(2years)
We could find out some small molecules which IC50 are less than 3 micro mol.
(2) Allergy (2007: atopic dermatitis)
In optimization of small molecules we designed some good compounds and we synthesized some of them.Funded by MITI (Ministry of Economy, Trade and Industry) $1M(1year)
(3) Oncology (2006-2010)
We could found out some indicate which is worth for optimization and this project is going to be founded by another grant.
Funded by MHLW(Ministry of Health, Labour and Welfare) through NIBIO(National Institute of Biomedical Innovation) $3M(5years)
(4) Infectious disease (2007-2011)
We could find out some inhibitors of PanC(protein which is necessary for Staphylococcus aureus).
Funded by MITI (Ministry of Economy, Trade and Industry) $3M(5year)
We always try to apply technology of new computational science and method of calculation.